| RD | Date | Opponent | Venue | Home/Away | Time |
| PM | Saturday, 1 March 2008 | North Ballarat | Frankston Park | ||
| PM | Saturday, 8 March 2008 | Box Hill | Frankston Park | ||
| PM | Saturday, 15 March 2008 | Casey | Frankston Park | ||
| PM | Saturday, 22 March 2008 | Port Melbourne | Port Melbourne | ||
| 1 | Sunday, Mar 30 | Northern Bullants | Frankston Park | Home | 2:00 PM |
| 2 | Saturday, Apr 05 | Casey Scorpions | Casey Fields | Away | 7:00 PM |
| 3 | Sunday, Apr 13 | Sandringham | Trevor Barker Beach Oval | Away | 2:00 PM |
| 4 | Sunday, Apr 20 | Collingwood | Frankston Park | Home | 2:00 PM |
| 5 | Split Round Bye | ||||
| 5 | Saturday, May 03 | Port Melbourne | TEAC Oval (ABC TV) | Away | 1:10 PM |
| 6 | Saturday, May 10 | Bendigo Bombers | QE Oval | Away | 7:00 PM |
| 7 | Sunday, May 18 | Werribee | Frankston Park | Home | 2:00 PM |
| 8 | Sunday, May 25 | Tasmania | Frankston Park | Home | 2:00 PM |
| SANFL vs. VFL State Representative Match - Saturday 31st May | |||||
| 9 | Saturday, Jun 07 | North Ballarat | AUSTAR Arena (ABC TV) | Away | 1:10 PM |
| 10 | Sunday, Jun 15 | Williamstown | Burbank Oval | Away | 2:00 PM |
| 11 | Sunday, Jun 22 | Box Hill Hawks | Frankston Park | Home | 2:00 PM |
| 12 | Sunday, Jun 29 | Coburg Tigers | Frankston Park | Home | 2:00 PM |
| 13 | Sunday, Jul 06 | Collingwood | MC Labour Park | Away | 2:00 PM |
| 14 | Saturday, Jul 12 | Werribee | Bartercard Oval (ABC TV) | Away | 1:10 PM |
| 15 | Split Round Bye | ||||
| 15 | Saturday, Jul 26 | Port Melbourne | Frankston Park (ABC TV) | Home | 1:10 PM |
| 16 | Sunday, Aug 03 | Bendigo Bombers | Frankston Park | Home | 2:00 PM |
| 17 | Saturday, Aug 09 | Tasmania | Aurora Stadium (AFL C/R) | Away | 10:40 AM |
| 18 | Sunday, Aug 17 | Casey Scorpions | Frankston Park | Home | 2:00 PM |
| 19 | Saturday, Aug 23 | Sandringham | Frankston Park | Home | 2:00 PM |
| 20 | Saturday, Aug 30 | Geelong | Skilled Stadium (AFL C/R) | Away | 10:40 AM |
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